Fishing upstream of Myf5

Fishing upstream: health and the social history.

It is now fashionable (even in the United States) for doctors to talk about social determinants of health. Polls show that access to healthy and affordable food, controlling drug misuse, and cleaning up the environment are seen as more important to people’s health than access to high quality medical care.Groups such as Health Leads train doctors to identify their patients’ social needs and to l...

Differential role of p300 and CBP acetyltransferase during myogenesis: p300 acts upstream of MyoD and Myf5.

Studies in tissue culture cells have implicated p300 and CBP acetyltransferases in myogenic regulatory factor (MRF) mediated transcription and terminal differentiation of skeletal muscle cells. However, in vivo data placing p300 and CBP on myogenic differentiation pathways are not yet available. In this report we provide genetic evidence that p300 but not CBP acetyltransferase (AT) activity is ...

Two cell lineages, myf5 and myf5-independent, participate in mouse skeletal myogenesis.

In skeletal muscle development, the myogenic regulatory factors myf5 and myoD play redundant roles in the specification and maintenance of myoblasts, whereas myf6 has a downstream role in differentiating myocytes and myofibers. It is not clear whether the redundancy between myf5 and myoD is within the same cell lineage or between distinct lineages. Using lineage tracing and conditional cell abl...

Allelic Variation of MYF5 Gene Detected in the Camelus bactrianus

The myogenic factors (MYF) 5 gene has been reported to contribute to muscle growth and development, therefore they are considered as candidate genes for growth and meat quality related traits. The MYF5 gene is expressed during proliferation of myoblasts and comprises 3 exons. To ascertain whether there is any variation in the camel MYF5 gene, we have used a polymerase chain reaction-single stra...

Ecosystem effects of fishing.